The use of cannabidiol to treat chronic pain dates back thousands of years. Still today, pain relief is the most common reason for the use of medical cannabis in the US.
The efficacy of CBD solutions in treating chronic pain stems from its interaction with the CB1 and CB2 receptors in our body.
- CB1 receptors are present in the pain pathway at the peripheral and central nervous systems, and are distributed in regions of the brain (mainly the thalamus and amygdala) that are involved in processing and regulating the subjective experience of pain. They are also present in the peripheral sensory nerve endings.
- CB2 receptors are expressed in several types of inflammatory cells, as well as B and T cells that are crucial for the healthy functioning of our immune system. Activation of CB2 receptors can generate a pain-relieving response in moment of intense pain caused by inflammation and neuropathic pain.
CBD Oil for Pain and Arthritis:
CBD has proven effective in improving pain across a number of conditions:
- Chronic pain. Researchers have concluded CBD to be effective in overall pain management for people experiencing arthritis, back pain, cancer-related pain, and muscle and bone pain caused by fibromyalgia.
- Neuropathic pain. Neuropathy is pain caused by damage to the nerves, and is associated with injuries such as herniated discs, and infections such as shingles. Studies have found CBD to help with chronic neuropathy pain.
- Cancer treatment relief. The National Cancer Institute lists CBD as a treatment for reducing common side effects of chemotherapy, including pain, vomiting, and lack of appetite. Studies on oral sprays combining CBD and THC have shown greater relief for patients using oral sprays together with opioids, than patients using opioids alone.
Migraine pain relief. A series of studies combining CBD and THC show effectiveness in reducing acute pain for people with migraines and cluster headaches.