Beyond the relief of physical conditions, CBD boasts benefits in addressing mental and emotional conditions, including anxiety management.
The anxiety-reducing effect of CBD is carried out in a few ways:
- Interaction with a number of receptors in the body known to regulate fear and anxiety-related behaviors, specifically CB1, 5-HT1A serotonin, and TRPV1.
- Activation of anxiety-reducing receptors, including A1 and A2A.
- Altering the shape of the GABA-A receptor, the main inhibitory neurotransmitter in the central nervous system, in a way that amplifies its natural calming effect. The sedating effects of Valium and other Benzodiazepines are also mediated by GABA receptor transmission.
- When looking at the brain activity of people who consume it, CBD has been shown to reduce activity in the left amygdala. As the amygdala has a central role in responses to stressful and arousing situations, its reduced activity is directly linked with the anxiety-reducing effects of CBD
Numerous studies exhibit the positive effects of CBD on a range of anxiety-related conditions and behaviors:
- General anxiety. The National Institute on Drug Abuse asserts that CBD has been shown to reduce subjects’ physiological signs of anxiety, including increased heart rate.
- Post traumatic stress disorder. Multiple studies have shown that CBD can alleviate symptoms of PTSD, including nightmares and the replaying of bad memories.
- Social anxiety disorder. Research participants with SAD experienced overall reduced anxiety levels after taking CBD orally. An additional study showed CBD effective in helping people with social anxiety give public speeches.